Friday, May 17, 2013

What is the buffer equation and how is it derived?

Let's say we have an acid (HA) and its conjugate base (A-) in a solution. The chemical formula is written as the following:


                                                      HA + H2O ↔ H3O+ + A-



The buffer equation (Henderson-Hasselbalch equation) is derived for the above acid-conjugate base pair as shown by the following equations:


The last equation is the buffer equation (Henderson-Hasselbalch equation) that is used for buffer calculation of an acid - conjugate base pair.

If we have a base (B) and its conjugate acid (BH+) then the chemical formula is:

                                                       B + H2O ↔ BH+ + OH-

and the derivation is the following:



The last equation in the above is the buffer equation for a base-conjugate acid pair. Note that in the above derivation we used the relation pKw = pH + pOH.

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