Solubility is the concentration of solute at saturation in a given solvent at a certain temperature. The solute can be solid (e.g. sodium chloride), liquid (e.g. ethanol) or gas (e.g. carbon dioxide). The solvent can be solid (e.g. iron in metal alloys), liquid(e.g. water), or gas (e.g. nitrogen gas in air). Solubility can be expressed as the volume of the solvent in which 1 g of the solute dissolves to form a saturated solution at a given temperature. In addition, solubility can be expressed as concentration in mg/ ml, molarity, molality, or % w/v (weight/ volume).
Solubility can be measured by determining the concentration of the saturated solution. In order to achieve saturation, an excess amount of the solute is added to the solvent (distilled water) and shaken for 24 hours or until equilibrium is achieved at a given temperature. The formed solution is filtered and its concentration (solubility) is measured using UV spectrometer or by HPLC analysis.
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Solubility can be measured by determining the concentration of the saturated solution. In order to achieve saturation, an excess amount of the solute is added to the solvent (distilled water) and shaken for 24 hours or until equilibrium is achieved at a given temperature. The formed solution is filtered and its concentration (solubility) is measured using UV spectrometer or by HPLC analysis.
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